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Medchemexpress LLC Tegaserod maleate | 189188-57-6 | 99.9% | C20H27N5O5 | 500 MG
Supplier: Medchemexpress LLC HY14153A500MG
Tegaserod maleate is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist, with pKis of 7.5, 8.4, and 7.0 for human recombinant 5-HT2A, 5-HT2B, and 5-HT2C receptors. This compound induces tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling, and decreases S6 phosphorylation. It exhibits anti-tumor activity and shows potential for irritable bowel syndrome (IBS) research.
- Orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist
- 5-HT2B receptor antagonist
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Exhibits anti-tumor activity
- Potential for irritable bowel syndrome (IBS) research
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