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Apexbio Technology LLC Telatinib (BAY 57-9352) 332012-40-5 5mg
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Catalog No. 5000095629
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Telatinib (BAY 57-9352 CAS 332012-40-5) is a selective small molecule inhibitor targeting VEGFR2 (IC50 6 nM) VEGFR3 (IC50 4 nM) c-Kit (IC50 1 nM) and PDGFR (IC50 15 nM) By blocking the kinase activity of these receptors key mediators of angiogenesis and vascular remodeling Telatinib disrupts signaling pathways implicated in tumor growth and progression In various tumor cell lines including MDA-MB-231 Colo-205 DLD-1 and H460 Telatinib suppresses VEGFR2 autophosphorylation and inhibits PDGF- -driven responses It is widely investigated in preclinical and clinical studies for cancer therapy including trials in advanced solid tumors and research on overcoming multidrug resistance via ABCG2 inhibition

Catalog No. 50-000-95629 Supplier Apexbio Technology LLC Supplier No. A85505
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Telatinib (BAY 57-9352 CAS 332012-40-5) is a selective small molecule inhibitor targeting VEGFR2 (IC50 6 nM) VEGFR3 (IC50 4 nM) c-Kit (IC50 1 nM) and PDGFR (IC50 15 nM) By blocking the kinase activity of these receptors key mediators of angiogenesis and vascular remodeling Telatinib disrupts signaling pathways implicated in tumor growth and progression In various tumor cell lines including MDA-MB-231 Colo-205 DLD-1 and H460 Telatinib suppresses VEGFR2 autophosphorylation and inhibits PDGF- -driven responses It is widely investigated in preclinical and clinical studies for cancer therapy including trials in advanced solid tumors and research on overcoming multidrug resistance via ABCG2 inhibition

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