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Cayman Chemical TelotrIstat EtIprate 10mg
Supplier: Cayman Chemical 2534210 MG
A prodrug form of telotristat; reduces levels of 5-HT in mouse jejunum and blood at 15-300 mg/kg; inhibits increases in IL-1β and IL-6 levels, histological damage in the colon, and weight loss in a mouse model of trinitrobenzene sulfonic acid-induced colitis at 200 mg/kg; reduces colonic levels of MPO, IL-1β, and IL-17, as well as worm burden, in mice infected with T. muris at 300 mg/kg
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