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Cayman Chemical TenapnorhydrochlorIde 10mg
Supplier: Cayman Chemical 3287510 MG
An orally bioavailable NHE-3 inhibitor (IC50 = 10 nM for the recombinant rat protein); inhibits intestinal fluid absorption in mouse jejunum, but not distal colon, in a closed intestine loop assay at 10 µM; lowers both the sodium and phosphate urinary-to-dietary ratio in a dose-dependent manner in rats; reverses loperamide-induced decreases in stool pellet numbers and water content and prevents loperamide-induced constipation in mice at 5 mg/kg
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