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Cayman Chemical Tenapanor (hydrochloride), Purity: ≥98%, CAS: 1234365-97-9, 10 mg
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Catalog No. 502950857
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An orally bioavailable NHE-3 inhibitor (IC50 = 10 nM for the recombinant rat protein); inhibits intestinal fluid absorption in mouse jejunum, but not distal colon, in a closed intestine loop assay at 10 µM; lowers both the sodium and phosphate urinary-to-dietary ratio in a dose-dependent manner in rats; reverses loperamide-induced decreases in stool pellet numbers and water content and prevents loperamide-induced constipation in mice at 5 mg/kg

Catalog No. 50-295-0857 Supplier Cayman Chemical Supplier No. 3287510 MG
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An orally bioavailable NHE-3 inhibitor (IC50 = 10 nM for the recombinant rat protein); inhibits intestinal fluid absorption in mouse jejunum, but not distal colon, in a closed intestine loop assay at 10 µM; lowers both the sodium and phosphate urinary-to-dietary ratio in a dose-dependent manner in rats; reverses loperamide-induced decreases in stool pellet numbers and water content and prevents loperamide-induced constipation in mice at 5 mg/kg

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