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Medchemexpress LLC Teneligliptin hydrobromide | 906093-29-6 | 99.8% | 628.86 | 1 ML
Supplier: Medchemexpress LLC HY14806A10MM/1ML
Teneligliptin hydrobromide is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor, demonstrating IC50s of 0.37 nM for human DPP-4 and 0.29 nM for rat DPP-4. This compound improves blood glucose levels and is utilized in research pertaining to type 2 diabetes mellitus.
- Prevents activation of the NLRP3 inflammasome and associated injury.
- Protects against hypoxia/reoxygenation-induced endothelial cell injury by reducing reactive oxygen species.
- Inhibits inflammation and apoptosis induced by doxorubicin.
- Ameliorates diabetic polyneuropathy and enhances pancreatic β-cell volume and insulin secretion.
- Attenuates myocardial hypertrophy, injury, and inflammatory response in diabetic models.
- Prevents obesity and obesity-related manifestations by boosting energy expenditure.
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