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Medchemexpress LLC Teneligliptin hydrobromide | 906093-29-6 | MFCD20279612 | ≥98.0% | 628.86 | 25 MG
Supplier: Medchemexpress LLC 25MGHY14806A
Teneligliptin hydrobromide is an orally active, potent, and highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor. It improves blood glucose levels and is utilized in research related to type 2 diabetes mellitus. The compound exhibits a unique 'J-shaped' structure, enabling it to bind to four subsites of DPP-4.
- Orally active and selective dipeptidyl peptidase-4 (DPP-4) inhibitor.
- Improves blood glucose levels.
- Used in research for type 2 diabetes mellitus.
- Exhibits a unique 'J-shaped' structure for effective DPP-4 binding.
- Prevents activation of the NLRP3 inflammasome and injury by increasing AMPK phosphorylation.
- Protects against hypoxia/reoxygenation-induced endothelial cell injury.
- Inhibits lipopolysaccharide-induced cytotoxicity and inflammation.
- Prevents high glucose and H2O2 induced USP22-SIRT1 downregulation.
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