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Medchemexpress LLC Teneligliptin hydrobromide hydrate | 1572583-29-9 | 99.97% | 426.58 | 25 MG
Supplier: Medchemexpress LLC 25MGHY14806B
Teneligliptin hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor with IC50s of 0.37 and 0.29 nM for human and rat DPP-4, respectively. It improves blood glucose levels and is utilized in research related to type 2 diabetes mellitus.
- Prevents activation of NLRP3 inflammasome and injury in primary mouse cardiomyocytes
- Protects against hypoxia/reoxygenation-induced endothelial cell injury
- Inhibits inflammation and apoptosis in H9c2 cells
- Attenuates myocardial hypertrophy and injury in diabetic cardiomyopathy mice
- Prevents obesity and related manifestations in high-fat diet-induced obesity models
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