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Apexbio Technology LLC Tenofovir 147127-20-6 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A52755.1
Tenofovir is an antiviral compound acting as an inhibitor of HIV reverse transcriptase specifically targeting RNA-dependent DNA polymerase to impede the replication cycle of HIV It interferes with the transcription process by competitively binding to the enzyme thereby preventing viral RNA from being transcribed into complementary DNA In vitro investigations indicate that Tenofovir inhibits viral replication as evidenced by an IC50 value of approximately 1 5 M in SIV-infected C-8166 cell assays Due to this inhibitory mechanism and antiviral activity against HIV Tenofovir is widely employed in biomedical and pharmacological research focused on HIV infection antiviral drug development and related studies involving reverse transcriptase enzymatic activity
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