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Medchemexpress LLC Tenofovir Disoproxil fumarate | 202138-50-9 | 99.7% | 635.51 | 1 ML
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Supplier:  Medchemexpress LLC HY1378210MM/1ML

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Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. It is used to treat HIV and chronic Hepatitis B.

  • Used to treat HIV and chronic hepatitis B
  • Shows cytotoxic effects on HK-2 cells
  • Diminishes ATP levels in HK-2 cells
  • Increases oxidative stress in HK-2 cells
  • Induces apoptosis via mitochondrial damage in HK-2 cells
  • Inhibits HIV replication in activated PBMCs
  • Exhibits synergistic antiretroviral activity with M48U1 formulation
  • Demonstrates dose-dependent activity during vaginal HIV challenge in BLT mice
  • Reduces HIV transmission in BLT mice
  • Induces dose-dependent decline in serum viremia in woodchucks

Catalog No. 50-003-51446


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