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Medchemexpress LLC Terephthalic acid | 100-21-0 | 99.99% | 166.13 | 50 G
Supplier: Medchemexpress LLC HYW01009850G
Terephthalic acid is an isomer and a precursor of polyester PET, used in clothing and plastics. It can also be utilized to build skin tumor models and promote excessive cell proliferation by disrupting the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway. In vivo, it can lead to bladder stone formation in animal models, particularly in weanling mice at higher doses.
- Isomer and precursor of polyester PET
- Used to build skin tumor models
- Promotes excessive cell proliferation
- Induces skin tumor formation
- Metabolized to form calcium terephthalate, potentially leading to bladder stone formation
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