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Medchemexpress LLC Tertiapin-Q | 910044-56-3 | 99.8% | 2452.00 | 1 MG
Supplier: Medchemexpress LLC HYP12751MG
Tertiapin-Q is a highly selective blocker of G protein-coupled inwardly rectifying potassium (GIRK1/4) heterodimer and renal outer medullary potassium channel (ROMK1/Kir1.1). It also potently and selectively blocks Kir3.1-Kir3.4 channels and calcium activated large conductance potassium channels. Tertiapin-Q significantly prolongs the atrial effective refractory period in control and rapid atrial pacing rabbits, with a greater effect in the latter. Additionally, it acts as a muscarinic acetylcholine receptor-operated K+ current (IK,Ach) blocker.
- Highly selective blocker of GIRK1/4 heterodimer and ROMK1 (Kir1.1)
- Potently blocks Kir3.1-Kir3.4 channels and calcium activated large conductance potassium channels
- Prolongs atrial effective refractory period
- Acts as a muscarinic acetylcholine receptor-operated K+ current blocker
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