Invitrogen™ Human TESK2, GST Tag Recombinant Protein

Catalog No.	Quantity
PV6418	10 μg
PV6419	100 μg
PV6420	1 mg

Catalog No. PV6418 Supplier Invitrogen™ Supplier No. PV6418

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Recombinant full-length human TESK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. , Validated in LanthaScreen™ Kinase Binding Assay, Protocols available for simple use and optimized performance, Multiple pack sizes available for convenient use Protein Form: Recombinant The gene accession number for TESK2 is NP_009101.2.

TESK2 or testis-specific kinase 2 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. The kinase domain of TESK2 is structurally similar to the kinase domain of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). TESK2 is predominantly expressed in testis and prostate and plays an important role in spermatogenesis. TESK2 phosphorylates cofilin specifically at Ser-3 and induces formation of actin stress fibers and focal adhesions.

Specifications

• Accession Number: Q96S53
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 0.1mM PMSF, 0.1mM EDTA, 10mM glutathione, 0.25mM DTT, 25% glycerol, 150mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 10420
• Molecular Weight (g/mol): 89.9 kDa
• Name: Human TESK2, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: dual specificity testis-specific protein kinase 2; TESK2; Testicular protein kinase 2; testis-specific kinase 2
• Common Name: TESK2
• Gene Symbol: TESK2
• Protein Length: 1-571
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: 1-571
• Content And Storage: Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol
  
  Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
• Assay Entry: Biochemical binding/kinetic
• Kinase Group: Serine/Threonine Kinase
• Target Entry: TESK2
• Expression System: Baculovirus
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Drug Discovery: Signal Transduction