Tetra-n-butylammonium fluoride trihydrate, 98%

Description

CAS: 87749-50-6 | C16H42FNO3 | 315.514 g/mol

Tetra-n-butylammonium fluoride trihydrate is used as a phase transfer catalyst, as a mild base and as a source of fluoride ion in organic solvents. It is also used as a deprotecting agent to remove silyl ether protecting groups. It acts as a reactant for the preparation of deprotecting agents, in preparation of cellulose derivatives, lipophilic peptides for DNA transfections and Dehydrobromination reactions. It plays an important role in the convertion of O-silylated enolates in to carbonyls in the presence of dimethyl sulfoxide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tetra-n-butylammonium fluoride trihydrate is used as a phase transfer catalyst, as a mild base and as a source of fluoride ion in organic solvents. It is also used as a deprotecting agent to remove silyl ether protecting groups. It acts as a reactant for the preparation of deprotecting agents, in preparation of cellulose derivatives, lipophilic peptides for DNA transfections and Dehydrobromination reactions. It plays an important role in the convertion of O-silylated enolates in to carbonyls in the presence of dimethyl sulfoxide.

Solubility
Soluble in water, terahydrofuran, dimethyl sulfoxide and acetonitrile.

Notes
Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 87749-50-6
• Molecular Formula: C16H42FNO3
• Molecular Weight (g/mol): 315.514
• MDL Number: MFCD00149981
• InChI Key: VEPTXBCIDSFGBF-UHFFFAOYSA-M
• Synonym: tetrabutylammonium fluoride trihydrate, tetra-n-butylammonium fluoride trihydrate, tetrabutylazanium fluoride trihydrate, tetrabutylammonium trihydrate fluoride, 1-butanaminium, n,n,n-tributyl-, fluoride, trihydrate, tetrabutylammonium ion trihydrate fluoride, tetra-n-butylammonium fluoride hydrate, bu4nf trihydrate, pubchem2275, pubchem4057
• PubChem CID: 11726816
• IUPAC Name: tetrabutylazanium;fluoride;trihydrate
• SMILES: CCCC[N+](CCCC)(CCCC)CCCC.O.O.O.[F-]

• Melting Point: 54°C to 60°C
• Odor: Odorless
• Linear Formula: [CH₃(CH₂)₃]₄NF·3H₂O
• Quantity: 50 g
• UN Number: UN2811
• Beilstein: 3761900
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water,terahydrofuran,dimethyl sulfoxide and acetonitrile.
• Formula Weight: 315.52 (261.47 Anhydrous)
• Percent Purity: 98%
• Chemical Name or Material: Tetra-n-butylammonium fluoride trihydrate

Safety and Handling

Hazard Category	H314-H335
Hazard Statement	GHS H Statement H300-H318-H315 Fatal if swallowed. Causes serious eye damage. Causes skin irritation.
Precautionary Statement	P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: III
EINECSNumber	207-057-2
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only