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Medchemexpress LLC Tetraethylammonium chloride | 56-34-8 | 98% | 5 G
Supplier: Medchemexpress LLC HYB17935G
Tetraethylammonium chloride is a non-selective potassium channel blocker. It also acts as a good substrate for organic cation transporter (OCTN1) and has demonstrated antitumor properties. In vitro studies show it inhibits proliferation and increases apoptosis in glioma cells, while in vivo it affects contractility of rat colon and rectum.
- Acts as a non-selective potassium channel blocker.
- Good substrate for organic cation transporter (OCTN1).
- Exhibits antitumor properties.
- Inhibits proliferation of C6 and 9L glioma cells.
- Increases apoptosis in C6 and 9L glioma cells.
- Elevates Bax/Bcl-2 protein ratio.
- Increases intracellular ROS in C6 and 9L cells.
- Increases amplitude and frequency of contractility of rat colon and rectum.
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