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Cayman Chemical Tetrazolyl GlycIn 10mg
SDP

Supplier:  Cayman Chemical 2840810 MG

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An NMDA receptor agonist (IC50 = 98 and 36 nM for [3H]CGS19755 and [3H]glutamate, respectively, in radioligand binding assays); It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED50 = 0.071 mg/kg); increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury when administered via intrastriatal injection at 5 µM

Catalog No. 50-293-9531


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