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Cayman Chemical tetrnor-PGEM-d6 50ug

Supplier: Cayman Chemical 31484050 UG

A bacterial metabolite with diverse biological activities active against a variety of bacteria (MICs 6 25 and 100 Ug/ml) and fungi (MICs 12 5-100 Ug/ml) inhibits proliferation of A549 lung HCT116 colon and HeLa cervical cancer cells (IC50s 0 3 0 6 and 0 3 UM respectively) and NIH373 fibroblasts (IC50 56 6 UM) but not MDA-MD-231 breast cancer cells (IC50 100 UM) forms a complex with Fe(II) and Fe(III) and the antiproliferative effect on HeLa cells is blocked by the addition of iron ions prevents apoptosis in the brain region of zebrafish larvae by 44 in a model of all-trans retinoic acid-induced neuronal cell death
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