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Medchemexpress LLC TFLLR-NH2(TFA) | 1313730-19-6 | 99.6% | 761.83 | 10 MG
Supplier: Medchemexpress LLC HYP0226A10MG
TFLLR-NH2(TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM, intended for research use. It stimulates concentration-dependent increases in intracellular calcium and promotes upregulation of E-cadherin expression in SW620 cells. In vivo, it can induce oedema and extravasation in various organs.
- Selective PAR1 agonist (EC50 of 1.9 μM)
- Induces concentration-dependent increases in intracellular calcium
- Upregulates E-cadherin expression in SW620 cells
- Stimulates secreted TGF-β1 in platelet cultures
- Can induce oedema and extravasation in animal models
- Stable for 2 years as powder at -80°C
- Stable for 6 months in solvent at -80°C
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