Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000426820

Medchemexpress LLC TFLLR-NH2(TFA) | 1313730-19-6 | 99.6% | 761.83 | 25 MG
SDP

Catalog No. 5000426820
Encompass_Preferred

TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. It stimulates concentration-dependent increases in [Ca2+]i, upregulates E-cadherin, and downregulates vimentin expression in SW620 cells. It also induces a dose-dependent increase of secreted TGF-β1 in activated platelets. In vivo, it causes marked and sustained oedema and Evans blue extravasation, and produces contraction and relaxation in rat duodenal smooth muscle.

  • Selective PAR1 agonist with an EC50 of 1.9 μM
  • Appears as a white to off-white solid
  • Soluble in DMSO and H2O at 100 mg/mL
  • Upregulates E-cadherin and downregulates vimentin expression
  • Induces dose-dependent increase of secreted TGF-β1
  • Stimulates oedema and Evans blue extravasation in vivo
  • Produces contraction and relaxation in rat duodenal smooth muscle

Catalog No. 50-004-26820 Supplier Medchemexpress LLC Supplier No. 25MGHYP0226A
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. It stimulates concentration-dependent increases in [Ca2+]i, upregulates E-cadherin, and downregulates vimentin expression in SW620 cells. It also induces a dose-dependent increase of secreted TGF-β1 in activated platelets. In vivo, it causes marked and sustained oedema and Evans blue extravasation, and produces contraction and relaxation in rat duodenal smooth muscle.

  • Selective PAR1 agonist with an EC50 of 1.9 μM
  • Appears as a white to off-white solid
  • Soluble in DMSO and H2O at 100 mg/mL
  • Upregulates E-cadherin and downregulates vimentin expression
  • Induces dose-dependent increase of secreted TGF-β1
  • Stimulates oedema and Evans blue extravasation in vivo
  • Produces contraction and relaxation in rat duodenal smooth muscle

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.