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Medchemexpress LLC Tfllr-nh2(tfa) | 1313730-19-6 | 99.6% | 761.83 | 5 MG
Supplier: Medchemexpress LLC HYP0226A5MG
TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM, intended for research use only. It appears as a white to off-white solid.
- Acts as a selective PAR1 agonist
- Stimulates concentration-dependent increases in [Ca2+]i in neurons
- Activated platelets upregulate E-cadherin and downregulate vimentin expression in SW620 cells
- Increases secreted TGF-β1 in platelet cultures
- Injection into rat paws stimulates marked and sustained oedema
- Stimulates Evans blue extravasation in various organs in wild-type mice
- Can induce both contraction and relaxation in rat duodenal smooth muscle
- Recommended storage for powder is -80°C for 2 years or -20°C for 1 year
- Recommended storage in solvent is -80°C for 6 months or -20°C for 1 month
- High solubility in DMSO and H2O (100 mg/mL)
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