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Cayman Chemical TG11-77hydrochlorIde 10mg

Supplier: Cayman Chemical 3018810 MG
An EP2 receptor antagonist (KB = 9.7 nM); selective for EP2 over DP1, EP4, and IP receptors (KBs = 7,320, 5,300, and >10,000 nM, respectively); inhibits the expression of genes encoding COX-2, IL-1β, and IL-6 induced by LPS and the EP2 receptor agonist ONO-AE1-259-01 in mouse BV-2 microglia expressing human EP2 receptors at 0.3 and 1 μM
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