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ABclonal Technology TGF beta induced TGFBI

Supplier: ABclonal Technology A2196420UL
This gene encodes an RGD-containing protein that binds to type I II and IV collagens The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion Mutations in this gene are associated with multiple types of corneal dystrophy
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