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Invitrogen™ Human TGFBR2, GST Tag Recombinant Protein

Catalog No. PV6123
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PV6123 1 mg
PV6122 10 μg
PR9154A 100 μg
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Catalog No. PV6123 Supplier Invitrogen™ Supplier No. PV6123
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Recombinant Protein

Transforming Growth Factor, beta receptor 2 (AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases. It is involved in the regulation of cell proliferation. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). TGFBR2 encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. TGFBR2 also has a pseudogene on chromosome 14.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P37173
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 150mM NaCl, 0.5mM EDTA, 2mM DTT, 50% glycerol, 0.02% NP-40 and no preservative; pH 7.5
Gene ID (Entrez) 7048
Molecular Weight (g/mol) 70.3 kDa
Name Human TGFBR2, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 1 mg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 1110020H15Rik; AAT3; AU042018; DNIIR; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; RIIDN; TAAD2; TbetaRII; TbetaR-II; TBR-II; tgf beta receptor 2; TGF-beta 2; TGF-beta receptor II; TGF-beta receptor type II; TGF-beta receptor type IIB; TGF-beta receptor type-2; TGFbeta RII; TGFbeta type II receptor; TGF-beta type II receptor; TGFbeta-RII; TGFBR2; Tgfbr2T; TGFR2; TGFR-2; transforming growth factor beta receptor 2; transforming growth factor beta receptor II; transforming growth factor beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor 2; transforming growth factor, beta receptor II; transforming growth factor, beta receptor II (70/80kDa); transforming growth factor, beta receptor II alpha; transforming growth factor, beta receptor II beta; transforming growth factor, beta receptor II delta; transforming growth factor, beta receptor II epsilon; transforming growth factor, beta receptor II gamma; transforming growth factor, beta receptor IIT; transforming growth factor-b type II receptor; transforming growth factor-beta receptor type II; transforming growth factor-beta type II receptor
Common Name TGFBR2
Gene Symbol TGFBR2
Kinase Family STKR Kinase Family
Protein Length 194-567
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 194-567
Content And Storage Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% NP-40, 2 mM DTT and 50% glycerol. Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Kinase Group Ser⁄Thr Kinases: TKL Group
Expression System Baculovirus
Protein Family Growth Factors & Receptors
Protein Form Truncated
Form Liquid
Protein Subtype TGFs (Transforming Growth Factors)
Research Category Drug Development
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