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Medchemexpress LLC TGFBR2/TGF-beta RII 2ug | 2ug
Supplier: Medchemexpress LLC HYP772292UG
TGFBR2/TGF-beta RII Protein collaborates with TGFBR1 to form a dedicated receptor for TGFB1 TGFB2 and TGFB3 It serves as a signal transducer orchestrating diverse physiological and pathological processes including cell cycle regulation mesenchymal cell dynamics wound healing matrix production immunosuppression and carcinogenesis Upon cytokine binding the receptor complex activates TGFBR1 through TGFBR2 phosphorylation initiating the canonical SMAD-dependent TGF-beta signaling cascade Additionally TGFBR2 participates in non-canonical SMAD-independent pathways TGFBR2/TGF-beta RII Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived TGFBR2/TGF-beta RII protein expressed by HEK293 with C-hFc labeled tag
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