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Medchemexpress LLC TH-6 | 3031349-25-1 | 95.0% | 429.44 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14902950MG

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TH-6 is a potent HDAC inhibitor that shows anti-tumor activity. It inhibits cell migration and invasion, and induces apoptosis and cell cycle arrest at G2/M phase.

  • Potent HDAC inhibitor with specific IC50s for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8.
  • Inhibits cell migration and invasion.
  • Induces apoptosis and cell cycle arrest at G2/M phase.
  • Shows anti-tumor activity in mice models.
  • Exhibits antiproliferative activities in various cancer cell lines and normal human lung cells.
  • Inhibits tubulin polymerization.
  • Increases expression of Ac-α-Tubulin and AC-Histone H3 in HepG2 cells.
  • Shows favorable liver microsomal stability in vitro.

Catalog No. 50-003-59526


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