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Medchemexpress LLC TH-6 | 3031349-25-1 | 95.0% | 429.44 | C22H24FN3O5 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY14902910MG

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TH-6 is a potent histone deacetylase (HDAC) inhibitor intended for research applications. It inhibits multiple HDAC isoforms, induces apoptosis, causes G2/M cell cycle arrest, and demonstrates antiproliferative and antitumor activity in preclinical models.

  • Potent HDAC inhibition with submicromolar to low micromolar IC50s.
  • Inhibits cell migration and invasion in cancer cell models.
  • Induces apoptosis and G2/M phase cell cycle arrest.
  • Inhibits tubulin polymerization (IC50 4.06 μM) and increases acetylated α-tubulin and histone H3 levels.
  • Supplied as a light yellow to khaki solid with 95.0% purity.
  • Molecular weight 429.44; formula C22H24FN3O5; CAS 3031349-25-1.
  • Soluble in DMSO at 50 mg/mL (requires warming and sonication).

Catalog No. 50-002-85568


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