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Medchemexpress LLC Thal-sns-032 | 2139287-33-3 | >98.0% | 869.02 g·mol⁻¹ | C40H52N8O10S2 | 1MG
SDP

Catalog No. 5000235251
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THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of the CDK-binding ligand SNS-032 linked to a thalidomide-derived cereblon (CRBN) E3 ligase ligand. It promotes CRBN-dependent ubiquitination and proteasomal degradation of CDK9 and is supplied as a high-purity research compound for in vitro target degradation and mechanistic studies.

  • Selective CDK9 degradation via cereblon recruitment.
  • Reported potency with EC50 ≈ 4 nM in cell-based assays.
  • High purity (≥98% by HPLC) suitable for research use.
  • Molecular weight 869.02 g·mol⁻¹ and defined molecular formula.
  • Designed for use in mechanistic and pharmacology studies of targeted protein degradation.

Catalog No. 50-002-35251 Supplier Medchemexpress LLC Supplier No. HY1239371MG
May include imposed supplier surcharges.
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THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of the CDK-binding ligand SNS-032 linked to a thalidomide-derived cereblon (CRBN) E3 ligase ligand. It promotes CRBN-dependent ubiquitination and proteasomal degradation of CDK9 and is supplied as a high-purity research compound for in vitro target degradation and mechanistic studies.

  • Selective CDK9 degradation via cereblon recruitment.
  • Reported potency with EC50 ≈ 4 nM in cell-based assays.
  • High purity (≥98% by HPLC) suitable for research use.
  • Molecular weight 869.02 g·mol⁻¹ and defined molecular formula.
  • Designed for use in mechanistic and pharmacology studies of targeted protein degradation.

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