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Cayman Chemical -ThalIdomIde 1g
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Supplier:  Cayman Chemical 146101 G

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A minor tobacco alkaloid an agonist of a4B2 and a6/a3B2B4 subunit-containing nAChRs (EC50s 6.1 and 3.6 UM respectively) selective for these nAChRs over a3B4 subunit-containing nAChRs or a7 nAChRs (EC50s 70.6 and 158.5 UM respectively) stimulates dopamine release from isolated rat brain synaptosomes (EC50s 1.76 and 100 UM respectively) has anxiolytic-like activity in zebrafish at 10 mg/L decreases disease severity in a mouse model of thyroglobulin CFA and M. tuberculosis immunization-induced moderate experimental autoimmune thyroiditis decreases food and nicotine self-administration in monkeys (ED50s 2.085 and 0.854 mg/kg respectively) has been used as a biomarker of tobacco use

Catalog No. 50-297-2909


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