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Medchemexpress LLC Thalidomide 4-fluoride | 835616-60-9 | 99.8% | 276.22 | 100 G
Supplier: Medchemexpress LLC HY41547100G
Thalidomide 4-fluoride, also known as Cereblon ligand 4, is a Thalidomide-based Cereblon ligand. It is utilized in the recruitment of CRBN protein, a component of the cullin-4 E3 ubiquitin ligase complex. This compound mediates the ubiquitination and subsequent proteasomal degradation of target proteins, and can be connected to other ligands to form PROTAC degraders.
- Thalidomide-based cereblon ligand.
- Used in the recruitment of CRBN protein.
- Targets cereblon (CRBN), a part of the E3 ubiquitin ligase complex.
- Mediates ubiquitination and proteasomal degradation of target proteins.
- Can be used to form PROTAC degraders.
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