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Medchemexpress LLC Thalidomide 4-fluoride | 835616-60-9 | 99.9 % | 276.22 | 50 G
Supplier: Medchemexpress LLC HY4154750G
Thalidomide 4-fluoride is a Thalidomide-based Cereblon ligand designed for the recruitment of CRBN protein. It can be linked to other ligands by a linker to form PROTAC degraders. In vitro, Thalidomide targets cereblon (CRBN), a ubiquitously expressed protein that is part of the cullin-4 E3 ubiquitin ligase complex. Cereblon mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
- Thalidomide-based cereblon ligand
- Used in the recruitment of CRBN protein
- Can be connected to other ligands to form PROTAC degraders
- Targets cereblon (CRBN), a protein involved in the cullin-4 E3 ubiquitin ligase complex
- Mediates ubiquitination and proteasomal degradation of target proteins
- High purity for reliable research
- Solid appearance, off-white to gray color
- Stable under recommended storage conditions
- Soluble in DMSO (200 mg/mL)
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