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Medchemexpress LLC Thalidomide-4-O-CH2-COO(t-Bu) | 1950635-36-5 | 99.26% | 388.37 | 100 MG
Supplier: Medchemexpress LLC HY42771100MG
Thalidomide-4-O-CH2-COO(t-Bu) is a t-Bu modified Thalidomide, which is the final step intermediate in the synthesis of Thalidomide-4-OH. It acts as a Cereblon ligand to recruit CRBN proteins. The t-Bu protecting group can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. It is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules.
- Acts as a Cereblon ligand to recruit CRBN proteins.
- The t-Bu protecting group can be removed under acidic conditions to participate in the synthesis of PROTAC molecules.
- Key intermediate in the synthesis of CRBN-based designed PROTAC molecules.
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