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Medchemexpress LLC Thalidomide-4-O-CH2-COO(t-Bu) | 1950635-36-5 | 99.3% | 388.37 | 25 MG
Supplier: Medchemexpress LLC 25MGHY42771
Thalidomide-4-O-CH2-COO(t-Bu) is a t-Bu modified thalidomide that functions as a Cereblon ligand, recruiting CRBN proteins. This compound serves as a final intermediate in the synthesis of Thalidomide-4-OH. Its t-Bu protecting group can be removed under acidic conditions, making it suitable for participation in PROTAC molecule synthesis and a key intermediate for CRBN-based designed PROTAC molecules.
- t-Bu modified thalidomide
- Intermediate in Thalidomide-4-OH synthesis
- Functions as a Cereblon ligand
- Recruits CRBN proteins
- t-Bu protecting group is removable under acidic conditions
- Key intermediate for CRBN-based PROTAC molecule synthesis
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