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Medchemexpress LLC Thalidomide-4-O-CH2-COO(t-Bu) | 1950635-36-5 | 99.3% | 388.37 | 50 MG
Supplier: Medchemexpress LLC HY4277150MG
Thalidomide-4-O-CH2-COO(t-Bu) is a t-Bu modified Thalidomide, serving as the final intermediate in the synthesis of Thalidomide-4-OH. It functions as a Cereblon ligand, recruiting CRBN proteins. The t-Bu protecting group can be removed under acidic conditions to facilitate the synthesis of PROTAC molecules. This compound is a crucial intermediate for synthesizing CRBN-based designed PROTAC molecules.
- Functions as a Cereblon ligand
- Recruits CRBN proteins
- t-Bu protecting group can be removed under acidic conditions
- Key intermediate for synthesizing CRBN-based designed PROTAC molecules
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