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Medchemexpress LLC Thalidomide-5-propargyl | 2226303-74-6 | 95.9% | 312.28 g·mol⁻¹ | C16H12N2O5 | 50 MG
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Supplier:  Medchemexpress LLC HYW45795050MG

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Thalidomide-5-propargyl is a propargyl-modified thalidomide derivative that acts as a cereblon (CRBN) ligand for use in targeted protein degradation research. The terminal alkyne enables click chemistry and triazole formation, making the compound a versatile intermediate for PROTAC synthesis and medicinal chemistry applications.

  • Functions as a cereblon ligand for CRBN recruitment.
  • Contains a terminal alkyne suitable for click chemistry.
  • Suitable as an intermediate in PROTAC synthesis.
  • Provided with high purity (95.87%).
  • Available in small research pack sizes (25 mg, 50 mg, 100 mg).
  • Chemical formula C16H12N2O5; Mw 312.28 g·mol⁻¹.

Catalog No. 50-002-81095


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