Medchemexpress LLC Thalidomide-o-amido-c4-n3 | 2098488-36-7 | 98.4% | 428.40 | C19H20N6O6 | 25 MG

Supplier:  Medchemexpress LLC HY10361525MG

Thalidomide-O-amido-C4-N3 is a thalidomide-derived cereblon ligand-linker conjugate containing an azide functional group. It is used as a building block in PROTAC design and as a click-chemistry reagent to attach CRBN ligands to alkyne-bearing partners, enabling targeted protein degradation applications.

• Azide functional group compatible with CuAAC and SPAAC click chemistry.
• Designed as a cereblon (CRBN) ligand-linker conjugate for PROTAC synthesis.
• High purity as supplied (LCMS ~98.4%).
• Soluble in DMSO (≥ 41 mg/mL) for in vitro formulation.
• In vivo formulation examples achieve ≥ 2.5 mg/mL in common solvents and vehicles.
• Store under inert atmosphere at 4°C; in solution store at -80°C for long-term stability.

Catalog No. 50-002-44809