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Medchemexpress LLC Thalidomide-O-C6-azide | 2411389-65-4 | 99.1% | 399.40 | 100 MG
Supplier: Medchemexpress LLC HY148556100MG
Thalidomide-O-C6-azide is a synthesized E3 ligase ligand-linker conjugate, incorporating the Thalidomide based cereblon ligand and a linker used in PROTAC technology. This click chemistry reagent contains an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules or strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. It is designed for research applications related to PROTACs, which utilize the ubiquitin-proteasome system to degrade target proteins.
- Incorporates cereblon ligand and a linker for PROTAC technology
- Click chemistry reagent with an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Designed for research in protein degradation via PROTACs
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