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Medchemexpress LLC Thalidomide-O-C6-azide | 2411389-65-4 | 99.1% | 399.40 | 50 MG
Supplier: Medchemexpress LLC HY14855650MG
Thalidomide-O-C6-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates a thalidomide-based cereblon ligand and a linker used in PROTAC technology. This product is also a click chemistry reagent, containing an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a thalidomide-based cereblon ligand
- Features a linker used in PROTAC technology
- Functions as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc)
- Allows strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Supports selective degradation of target proteins through PROTACs
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