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Medchemexpress LLC Thalidomide-O-COOH | 1061605-21-7 | MFCD31560477 | 99.9% | 332.27 g·mol⁻¹ | C15H12N2O7 | 1 G
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Supplier:  Medchemexpress LLC HY1035971G

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Thalidomide-O-COOH is a thalidomide-derived small-molecule ligand that recruits the CRBN E3 ubiquitin ligase and is commonly used as the E3 ligase component in PROTAC design and other chemical biology applications.

  • Used as a cereblon (CRBN) E3 ligase ligand for PROTAC construction.
  • CAS number 1061605-21-7; molecular formula C15H12N2O7; molecular weight 332.27 g·mol⁻¹.
  • Reported high purity suitable for research and synthesis workflows.
  • Functional handle (carboxylic acid) enables conjugation to linkers and building blocks.
  • Supplied as a solid for storage and handling in synthetic and analytical protocols.

Catalog No. 50-002-44819


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