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Medchemexpress LLC Thalidomide-PEG2-C2-NH2 hydrochloride | 2245697-87-2 | 99.9% | 440.88 g·mol⁻1 | C19H25ClN4O6 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY129703B5MG

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Thalidomide-PEG2-C2-NH2 hydrochloride is a thalidomide-based cereblon E3 ligase ligand-linker conjugate provided as the hydrochloride salt for research use. It combines a thalidomide cereblon-binding moiety with a two-unit polyethylene glycol spacer and a C2 amino termination, designed for incorporation into PROTAC constructs and linker chemistry in targeted protein degradation studies.

  • Provides a thalidomide-derived cereblon binding motif suitable for E3 ligase recruitment.
  • Contains a PEG2 spacer to improve solubility and linker flexibility.
  • Terminates in a C2 amino handle for straightforward conjugation chemistry.
  • Supplied as the hydrochloride salt for enhanced stability and handling.
  • Characterized with reported molecular weight and purity for research applications.

Catalog No. 50-002-63153


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