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Medchemexpress LLC Thalidomide-piperazine-PEG2-NH2 diTFA | 00-00-0 | 99.7% | C27H33F6N5O10 | 10MG
SDP

Catalog No. 5000260685
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Thalidomide-Piperazine-PEG2-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates a thalidomide-derived cereblon (CRBN) ligand and a PEG2-piperazine amino linker. Supplied as the bis(trifluoroacetate) salt, it is designed as a building block for assembling heterobifunctional degraders (PROTACs) to recruit CRBN and enable targeted protein degradation.

  • Incorporates thalidomide-based cereblon ligand for CRBN recruitment.
  • Contains a PEG2-piperazine linker with a terminal primary amine for conjugation chemistry.
  • Supplied as the bis(trifluoroacetate) salt to aid handling and solubility.
  • High purity suitable for synthesis (99.7%).
  • Water solubility up to 50 mg/mL with ultrasonic assistance.
  • Store sealed at 4°C, away from moisture.

Catalog No. 50-002-60685 Supplier Medchemexpress LLC Supplier No. HY138788A10MG
May include imposed supplier surcharges.
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Thalidomide-Piperazine-PEG2-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates a thalidomide-derived cereblon (CRBN) ligand and a PEG2-piperazine amino linker. Supplied as the bis(trifluoroacetate) salt, it is designed as a building block for assembling heterobifunctional degraders (PROTACs) to recruit CRBN and enable targeted protein degradation.

  • Incorporates thalidomide-based cereblon ligand for CRBN recruitment.
  • Contains a PEG2-piperazine linker with a terminal primary amine for conjugation chemistry.
  • Supplied as the bis(trifluoroacetate) salt to aid handling and solubility.
  • High purity suitable for synthesis (99.7%).
  • Water solubility up to 50 mg/mL with ultrasonic assistance.
  • Store sealed at 4°C, away from moisture.

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