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AG Scientific Inc Thapsigargin, 1 MG
Supplier: AG Scientific Inc T10141MG

Thapsigargin is a sesquiterpene lactone that is known to inhibit sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA). Through the inhibition of SERCA, thapsigargin promotes the release and eventual depletion of intracellular calcium reserves, leading in turn to calcium influx. Thapsigargin's ability to regulate calcium influx has been shown to affect several physiological functions. This lactone is known to induce apoptosis by disrupting the ordinary organization of cytoskeletal structures.CAS Number: 67526-95-8Molecular Weight: 650.8Chemical Formula: C34H50O12Solubility: Clear and colorless solution at 10 mg/mL of CH3CNStorage Temperature: -20CResearch or further manufacturing use only, not for food or drug use.
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