Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thapsigargin, 95%

Catalog No. AAJ62866MCR
Click to view available options
Quantity:
1 mg
5 mg
10 mg

CAS: 67526-95-8 | C34H50O12 | 650.76 g/mol

Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. It is also used as an inducer of stored Ca2+ release.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. It is also used as an inducer of stored Ca2+ release.

Solubility
Soluble in DMSO (20 mg/ml), ethanol (20 mg/ml), and acetone.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 67526-95-8
Molecular Formula C34H50O12
Molecular Weight (g/mol) 650.76
MDL Number MFCD00083511
InChI Key IXFPJGBNCFXKPI-FSIHEZPISA-N
PubChem CID 126969181
SMILES CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)C(\C)=C/C)C(C)=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(C)=O)[C@@H]12)OC(=O)CCC

Specifications

Color White
Quantity 1 mg
Sensitivity Light sensitive
Merck Index 14,9272
Synonym thapsigargin, unii-z96bq26rzd, z96bq26rzd, chembl96926, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid, 6-acetyloxy-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy azuleno 4,5-b furan-7-yl ester, 3s-3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha z ,9balpha, tg1, --thapsigargin, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta,6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid 3s-3alpha, 3abeta, 4alpha,6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester
Solubility Information Soluble in DMSO (20mg/ml),ethanol (20mg/ml),and acetone.
IUPAC Name [(3S,3aR,4S,6S,6aS,7S,8S,9bR)-6-acetyloxy-4-butanoyloxy-3,3a-dihydroxy-3,6,9-trimethyl-8-(2-methylbut-2-enoyloxy)-2-oxo-4,5,6a,7,8,9b-hexahydroazuleno[4,5-b]furan-7-yl] octanoate
Formula Weight 650.75
Percent Purity 95%
Physical Form Solid Film
Chemical Name or Material Thapsigargin
Show More Show Less
Hazard Category H315-H319-H334-H335
Hazard Statement GHS H Statement
H334-H335-H315-H319
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.
Precautionary Statement P261-P264b-P271-P280-P285-P302+P352-P304+P340-P305+P351+P338-P332+P313-P342+P311-P362-P501c
RTECSNumber RH0325700
TSCA No
Recommended Storage Store at -20°C; Store under Nitrogen

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.