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Bachem (Gln22)-Amyloid Beta Protein (1-40) Trifluoroacetate
SDP

Supplier:  Bachem 4039928.1000

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(Gln22)-Amyloid Beta Protein (1-40) Trifluoroacetate, H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gln-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH, 144410-00-4, C194H296N54O57S, Mr 4328.88, 1mg. Amyloid b-Protein (1-40) E22Q, Amyloid b-Protein (1-40) Dutch Mutation, [Gln22] b-Amyloid (1-40). The Dutch mutation (E22Q) of amyloid b-peptide aggregates more readily than the wild-type peptide and the resulting fibrils show increased neurotoxicity. The mutant peptide E22Q induced apoptosis of cerebral endothelial cells at a concentration of 25 μm, whereas WT Ab 1-40 and the Italian mutant E22K showed no effect.

Catalog No. 50-194-6606


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