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Bachem Fmoc-Orn(Dde)-OH

Supplier: Bachem 4027859.0005
Fmoc-Orn(Dde)-OH, 269062-80-8, C30H34N2O6, Mr 518.61, 5g. The Nd-protecting group Dde is orthogonal to both Fmoc and Boc which allows on-resin modification of ornithine side chains during Fmoc/tBu-based SPPS. The applications of Dde side-chain protection include synthesis of branched or di-epitopic peptides, preparation of MAP core molecules and lipo-MAPS, the synthesis of cyclic peptides, TASP molecules, and templates for combinatorial chemistry and synthetic proteins. Dde can be cleaved by 2% hydrazine in DMF.
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