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Bachem (Pyr1)-Apelin-13 (human, bovine, mouse, rat) Trifluoroacetate

Supplier: Bachem 4029110.0005
(Pyr1)-Apelin-13 (human, bovine, mouse, rat) Trifluoroacetate, Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, 217082-60-5, C69H108N22O16S, Mr 1533.82, 5mg. (Glp1)-Apelin-13, human, bovine. The pyroglutamyl form of apelin-13 exhibited a high activity with an EC50 value of 0.30 nM. pERPRLSHKGPMPF is probably the final product of the post-translational modification of apelin and the biologically active endogenous ligand. (Pyr1)-Apelin-13 has been identified as the predominant apelin isoform in the human heart. Pyr-Apelin-13 stimulates glucose utilization in normal and obese insulin-resistant mice. It could be required for the maintenance of insulin sensitivity.
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