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New England Biolabs, Inc. Thermostable OGG - 500 units
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Supplier:  New England Biolabs, Inc. M0464S

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Thermostable OGG is an archaeal 8-oxoguanine (8oxoG) DNA glycosylase which acts both as aN-glycosylase and an AP-lyase. TheN-glycosylase activity releases the damaged purine (8-oxoguanine) from double stranded DNA, generating an apurinic (AP) site. The AP-lyase activity cleaves 3' to the AP site leaving a 5' phosphate and a 3'-phospho-alpha, beta-unsaturated aldehyde. Unlike some other DNA glycosylases, Thermostable OGG specifically recognizes and cleaves only 8oxoG and no other modified bases.

Catalog No. 50-233-6248


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