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Thiazole, 99%
Description
Thiazole is used as a flavoring agent and in the preparation of dyes and rubber accelerators. It serves as a component of the vitamin thiamine (B1). It acts as a protected formyl group used in natural product synthesis. It reacts with alkyl lithium and Grignard’s reagent to prepare organometallic complexes. It is involved in the electrophilic aromatic substitution and nucleophilic aromatic substitution at C-5 and C-2 positions respectively. Further, it undergoes alkylation reaction to get thiazolium cation, which is used as a catalyst in the Stetter reaction and the Benzoin condensation. In addition to this, it is involved in the preparation of alagebrium.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Thiazole is used as a flavoring agent and in the preparation of dyes and rubber accelerators. It serves as a component of the vitamin thiamine (B1). It acts as a protected formyl group used in natural product synthesis. It reacts with alkyl lithium and Grignard’s reagent to prepare organometallic complexes. It is involved in the electrophilic aromatic substitution and nucleophilic aromatic substitution at C-5 and C-2 positions respectively. Further, it undergoes alkylation reaction to get thiazolium cation, which is used as a catalyst in the Stetter reaction and the Benzoin condensation. In addition to this, it is involved in the preparation of alagebrium.
Solubility
Soluble in ethanol and ether. Slightly soluble in water.
Notes
Air and light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.
Specifications
Specifications
| Melting Point | -33°C |
| Density | 1.2 |
| Boiling Point | 117°C to 118°C |
| Flash Point | 22°C (71°F) |
| Odor | Unpleasant |
| Refractive Index | 1.539 |
| Quantity | 25 g |
| UN Number | UN1993 |
| Beilstein | 103852 |
| Sensitivity | Air and light sensitive |
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Safety and Handling
| Hazard Category | H226-H302 |
| Hazard Statement | GHS H Statement H225-H302-H319 Highly flammable liquid and vapor. Harmful if swallowed. Causes serious eye irritation. |
| Precautionary Statement | P210-P233-P240-P241-P242-P243-P264b-P270-P280-P301+P312-P303+P361+P353-P330-P370+P378q-P501c |
| DOTInformation | Hazard Class: 3; Packaging Group: III |
| EINECSNumber | 206-021-3 |
| RTECSNumber | XJ1290000 |
| TSCA | Yes |
| Recommended Storage | Ambient temperatures; Store under Nitrogen |
RUO – Research Use Only
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