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Cayman Chemical ThIocolchIcosIde 10mg
SDP

Supplier:  Cayman Chemical 3582110 MG

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A GABAA receptor antagonist; inhibits GABAA receptor mediated currents in Purkinje cells isolated from rat cerebellum (IC50 = 0.15 µl); binds strychnine-sensitive glycine receptors in isolated rat spinal cord (IC50 = 1.58 µM); inhibits cell growth in a panel of cancer cell lines at 25-100 µM; inhibits anti-apoptotic proteins Bcl-2, XIAP, Mcl-1, Bcl-xL, cIAP-1, and cIAP-2 in KBM5 cells; inhibits TNF-α-induced NF-κB activation and IκBα degradation in KBM5 cells

Catalog No. 50-291-2718


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