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Apexbio Technology LLC Thiolutin(Synonyms: Acetopyrrothin, Farcinicin, Aureothricin, Antibiotic 810, Pyrrothine, Nocathiacin), 10mg, CAS: 32087.

Supplier: Apexbio Technology LLC A454710
Thiolutin (CAS 87-11-6) is a microbial-derived antibiotic known to inhibit RNA polymerase activity in bacteria It also interferes with the adhesion process of human umbilical vein endothelial cells (HUVECs) to vitronectin displaying an IC value of approximately 0 83 mM and subsequently reduces cellular paxillin expression Through these actions thiolutin effectively diminishes tumor cell-induced angiogenesis making it a useful tool compound in research exploring transcription regulation cell adhesion processes and tumor-related angiogenic mechanisms
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