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Medchemexpress LLC Thiolutin (Acetopyrrothin) | 87-11-6 | 10 MG
Supplier: Medchemexpress LLC HYN671210MG
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic and a potent inhibitor of bacterial and yeast RNA polymerases. Produced by Streptomyces, it functions as a dual inhibitor of BRCC36 and the NLRP3 inflammasome, demonstrating anti-inflammatory and anti-angiogenic properties.
- Sulfur-containing antibiotic
- Potent inhibitor of bacterial and yeast RNA polymerases
- Inhibits AMSH and Rpn11
- Dual inhibitor of BRCC36 and the NLRP3 inflammasome
- Anti-inflammatory effects
- Inhibits HCC growth by suppressing BRCC36 and HMGCR interaction
- Attenuates pyroptosis and NLRP3 inflammasome activation
- Alleviates renal injury and inflammatory processes in IgAN
- Acts as an anti-angiogenic compound
- Eases Doxorubicin-induced cardiotoxicity
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