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Thiolutin, Tocris Bioscience™

Catalog No. 15671
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15-671 1 mg
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Catalog No. 15-671 Supplier R&D Systems Supplier No. 1567/1
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Description

Bacterial RNA polymerase inhibitor

Antibiotic; inhibits bacterial RNA polymerase. Inhibits adhesion of HUVEC cells to vitronectin (IC50 = 0.83 mM) and subsequently reduces paxillin levels. Suppresses tumor cell-induced angiogenesis.

Chemical Identifiers

CAS 87-11-6
Molecular Formula C8H8N2O2S2
Molecular Weight (g/mol) 228.284
InChI Key MHMRAFONCSQAIA-UHFFFAOYSA-N
Synonym thiolutin, acetopyrrothin, acetopyrrothine, n-4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo 4,3-b pyrrol-6-yl acetamide, 3-acetamido-5-methylpyrrolin-4-one 4,3-d-1,2-dithiole, 6-acetamido-4-methyl-1,2-dithiolo 4,3-b pyrrol-5 4h-one, 6-acetylamino-4-methyl-1,2-dithiolo 4,3-b pyrrol-5 4h-one, 1,2-dithiolo 4.3-b pyrrol-5 4h-one, 6-acetamido-4-methyl
PubChem CID 6870
IUPAC Name N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide
SMILES CC(=O)NC1=C2C(=CSS2)N(C1=O)C

Specifications

Quantity 1 mg
Formula Weight 228.28
Percent Purity >98%
Chemical Name or Material Thiolutin

Safety and Handling

Recommended Storage Desiccate at -20°C
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